Aldactone (Spironolactone)

What is Aldactone (Spironolactone)?

Aldactone is a brand name for the compound spironolactone. It is made in a lab and comes as a tablet.

It sits in a group called potassium-sparing diuretics. A diuretic is a compound that makes the kidneys pass more water.

It blocks a hormone called aldosterone. A hormone is a chemical signal. Aldosterone acts on cells in the kidney.

What researchers study it for

• Blocking the aldosterone receptor. Labs study how it blocks the aldosterone receptor in kidney cells.
• Sodium and water flow. Studies measure how much sodium and water leave in urine.
• Potassium levels in tests. Labs measure potassium levels, since this compound spares potassium.
• Compared with other diuretics. Studies line it up against furosemide, a loop diuretic.

What you get

One bottle of 50 tablets. Each tablet holds 50 mg of spironolactone. Study notes describe short test windows of 2–3 days.

How to store it

Keep the bottle in a cool, dry place. Keep it away from direct light.

Words you might not know

• Aldosterone — a hormone that acts on cells in the kidney.
• Receptor — a docking point on a cell where a hormone attaches.
• Diuretic — a compound that makes the kidneys pass more water.
• Potassium-sparing — a diuretic that holds potassium in rather than losing it.
• mg — milligram, a small unit of weight.

Sold for laboratory research only. Not for human consumption.